Protection fromStaphylococcus aureusmastitis associated with poly-N-acetyl [beta]-1,6 glucosamine specific antibody production using biofilm-embedded bacteria

• Published in: Vaccine Vol. 27; no. 17; p. 2379
• Main Authors: Pérez, MM, Prenafeta, A, Valle, J, Penadés, J, Rota, C, Solano, C, Marco, J, Grilló, MJ, Lasa, I, Irache, JM, Maira-Litran, T, Jiménez-Barbero, J, Costa, L, Pier, GB, de Andrés, D, Amorena, B
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Limited 14.04.2009
• Subjects: Aluminum; Antigens; Bacteria; Bacteriology; Biofilms; Immunology; Laboratory animals; Production capacity; Saccharides; Sheep; Slime; Staphylococcus infections; Vaccines

Staphylococcus aureusvaccines based on bacterins surrounded by slime, surface polysaccharides coupled to protein carriers and polysaccharides embedded in liposomes administered together with non-biofilm bacterins confer protection against mastitis. However, it remains unknown whether protective anti...