Intestinal and Systemic Inflammatory Responses Are Positively Associated with Sulfidogenic Bacteria Abundance in High-Fat-Fed Male C57BL/6J Mice1,2

• Published in: The Journal of nutrition Vol. 144; no. 8; p. 1181
• Main Authors: Shen, Wan, Wolf, Patricia G, Carbonero, Franck, Zhong, Wei, Reid, Tanya, Gaskins, H Rex, McIntosh, Michael K
• Format: Journal Article
• Language: English
• Published: Bethesda American Institute of Nutrition 01.08.2014
• Subjects: Bacteria; Diabetes; Diet; Gene expression; Insulin resistance; Nitrogen; Rodents

Recent studies have highlighted the relation between high-fat (HF) diets, the gut microbiota, and inflammation. However, the role of sulfidogenic bacteria in mediating these effects has been explored only recently. Therefore, we tested the hypothesis that an HF diet rich in saturated fat stimulates...