Rapid corticosteroid effect on [beta]2-adrenergic airway and airway vascular reactivity in patients with mild asthma

• Published in: Journal of allergy and clinical immunology Vol. 121; no. 3; p. 700
• Main Authors: Mendes, Eliana S, Horvath, Gabor, Campos, Michael, Wanner, Adam
• Format: Journal Article
• Language: English
• Published: St. Louis Elsevier Limited 01.03.2008
• Subjects: Asthma; Blood pressure; Drug dosages; Hypotheses; Rodents; Smooth muscle

Background Long-term glucocorticoid therapy has been suggested to improve airway and airway vascular smooth muscle responsiveness to inhaled β2-agonists in patients with asthma. Objective We sought to assess whether a single dose of an inhaled glucocorticoid acutely potentiates β2-adrenergic airway...