Activation of [beta]-catenin/TCF targets following loss of the tumor suppressor SNF5

• Published in: Oncogene Vol. 33; no. 7; p. 933
• Main Authors: Mora-blanco, E L, Mishina, Y, Tillman, E J, Cho, Y-j, Thom, C S, Pomeroy, S L, Shao, W, Roberts, C W M
• Format: Journal Article
• Language: English
• Published: New York Nature Publishing Group 13.02.2014
• Subjects: Cancer; Chromatin; Epigenetics; Gene expression; Mutation; Signal transduction

The SWI/SNF chromatin remodeling complex is a master regulator of developmental cell-fate decisions, although the key target pathways are poorly characterized. Here, we interrogated the contribution of the SWI/SNF subunit and tumor suppressor SNF5 to the regulation of developmental pathways using co...