Lipopolysaccharide induced protection against sulfur mustard cytotoxicity in RAW264.7 cells through generation of TNF-[alpha]

• Published in: Journal of toxicological sciences Vol. 35; no. 3; p. 345
• Main Authors: Allon, Nahum, Chapman, Shira, Shalem, Yoav, Brandeis, Rachel, Avi Weissman, Ben, Amir, Adina
• Format: Journal Article
• Language: English
• Published: Suita Japan Science and Technology Agency 01.05.2010

Sulfur mustard (HD), a very potent alkylating agent and lipopolysacchride (LPS), are both well characterized inflammatory factors. We have found that concomitant exposure of murine macrophage cells (RAW264.7) to LPS and HD induced protection against HD induced cytotoxicity. Both HD and LPS induce re...