Further Study on the Two Pivotal Parts of Hlg2 for the Full Hemolytic Activity of Staphylococcal [gamma]-Hemolysin

• Published in: Bioscience, biotechnology, and biochemistry Vol. 62; no. 9; p. 1745
• Main Authors: YOKOTA, Kenji, SUGAWARA, Noriko, NARIYA, Hirofumi, KANEKO, Jun, TOMITA, Toshio, KAMIO, Yoshiyuki
• Format: Journal Article
• Language: English
• Published: Tokyo Oxford University Press 01.09.1998

Staphylococcal γ-hemolysin consists of LukF of 34 kDa and Hlg2 (or HγII) of 32 kDa, which cooperatively lyse human and rabbit erythrocytes. Our previous data showed that the 5-residue segment K23R24L25A26I27 of Hlg2 is pivotal for the hemolytic activity [Nariya, H. and Kamio, Y., Biosci. Biotechnol....