Synthesis and Application of N-Tosyl Piperidinyl-Containing [alpha]-Aminophosphonates

• Published in: Phosphorus, sulfur, and silicon and the related elements Vol. 188; no. 8; p. 1026
• Main Authors: Jiang, Zhifu, Zhao, Jian, Gao, Beibei, Chen, Shuo, Qu, Wenyan, Mei, Xiangdong, Rui, Changhui, Ning, Jun, She, Dongmei
• Format: Journal Article
• Language: English
• Published: Abingdon Taylor & Francis Ltd 01.08.2013
• Subjects: Crystal structure

A series of novel (4[variant prime]-tosyl) piperidin-4-yl containing α-aminophosphonates were synthesized by a one-pot reaction, efficiently catalyzed by magnesium perchlorate, under solvent-free conditions from 1-tosylpiperidin-4-one, substituted aromatic amines, and diethyl phosphite (DEP). The sy...