Differential role of psoriasin (S100A7) in estrogen receptor [alpha] positive and negative breast cancer cells occur through actin remodeling

• Published in: Breast cancer research and treatment Vol. 138; no. 3; p. 727
• Main Authors: Sneh, Amita, Deol, Yadwinder S, Ganju, Akaansha, Shilo, Konstantin, Rosol, Thomas J, Nasser, Mohd W, Ganju, Ramesh K
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Nature B.V 01.04.2013
• Subjects: Breast cancer; Cancer research; Cancer therapies; Cellular biology; Epidermal growth factor; Metastasis; Proteins

Psoriasin (S100A7) is a calcium-binding protein that has shown to be highly expressed in high-grade ductal carcinoma in situ (DCIS) and a subset of invasive breast cancers. However, its role in invasion and metastasis is not very well known. In this study, we have shown that S100A7 differentially re...