HSP72 Protects Cells from ER Stress-induced Apoptosis via Enhancement of IRE1[alpha]-XBP1 Signaling through a Physical Interaction e1000410

Endoplasmic reticulum (ER) stress is a feature of secretory cells and of many diseases including cancer, neurodegeneration, and diabetes. Adaptation to ER stress depends on the activation of a signal transduction pathway known as the unfolded protein response (UPR). Enhanced expression of Hsp72 has...

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Bibliographic Details
Published inPLoS biology Vol. 8; no. 7
Main Authors Gupta, Sanjeev, Deepti, Ayswaria, Deegan, Shane, Lisbona, Fernanda, Hetz, Claudio, Samali, Afshin
Format Journal Article
LanguageEnglish
Published San Francisco Public Library of Science 01.07.2010
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