HSP72 Protects Cells from ER Stress-induced Apoptosis via Enhancement of IRE1[alpha]-XBP1 Signaling through a Physical Interaction e1000410
Endoplasmic reticulum (ER) stress is a feature of secretory cells and of many diseases including cancer, neurodegeneration, and diabetes. Adaptation to ER stress depends on the activation of a signal transduction pathway known as the unfolded protein response (UPR). Enhanced expression of Hsp72 has...
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Published in | PLoS biology Vol. 8; no. 7 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
San Francisco
Public Library of Science
01.07.2010
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Subjects | |
Online Access | Get full text |
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