P-284: Combined effects on vascular wall characteristics of the ACE I/D polymorphism and mutations of the A-B-[Gamma] adducin genes

• Published in: American journal of hypertension Vol. 14; no. S1; p. 123A
• Main Authors: Balkestein, Elisabeth J, Staessen, Jan A, Wang, Ji Guang, Barlassina, Cristina, Bianchi, Giuseppe, Van Bortel, Luc M, Struijker Boudier, Harry A
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.04.2001

We recently found that the intima-media thickness (IMT) of the muscular femoral artery but not the elastic carotid artery, increased with the number of D alleles of the angiotensin-converting enzyme gene (ACE/D). This increase was restricted to carriers of the D allele also having the α-adducin Trp...