Biosensors

• Main Author: Evtugyn, Gennady
• Format: eBook
• Language: English
• Published: Berlin, Heidelberg Springer Berlin / Heidelberg 2013
• Edition: 1
• Subjects: Biosensors; Detectors

Covering all the essentials from biochemical recognition to the latest MEMS systems, this book on biosensors and their applications includes a wealth of case studies. Written by a leading expert on the subject, it includes a chapter on likely future advances.

Table of Contents:

• Intro -- Preface -- Abbreviation List -- Contents -- 1 Introduction and Overview of History -- 1.1…Short Biosensor History -- 1.2…Biosensor Classification -- References -- 2 Biochemical Components Used in Biosensor Assemblies -- 2.1…Enzymes -- 2.2…Antibodies -- 2.3…Protein/Peptide Receptors -- 2.4…Nucleic Acids -- 2.5…Whole Cells as Biosensing Elements -- 2.6…Immobilization of Biochemical Elements of Biosensors -- 2.6.1 General Requirements for Immobilization Techniques -- 2.6.2 Physical Immobilization -- 2.6.3 Covalent Immobilization -- References -- 3 Biosensor Signal Transducers -- 3.1…Electrochemical Transducers -- 3.1.1 Potentiometric Sensors -- 3.1.2 Voltammetric Sensors -- 3.1.3 Conductometric and Impedimetric Devices -- 3.2…Optical Transducers -- 3.2.1 Optosensors -- 3.2.2 Bioluminescence and Electrogenerated Luminescence Devices -- 3.2.3 Surface Plasmon Resonance and SERS -- 3.3…Other Techniques -- 3.3.1 Quartz Crystal Microbalances -- 3.3.2 Calorimetric Biosensors -- 3.3.3 MEMS Systems -- References -- 4 How Does It Work? Case Studies -- 4.1…The Biggest Success: Glucose Meters -- 4.2…From Chemical Weapons Toward Pesticides: Anticholinesterase Sensing -- 4.3…Immunosensors Versus Test Strips: Hapten Determination -- 4.4…DNA Chips: The Human Genome Project and More -- 4.5…Toxicity Bioassay: Microtoxreg Related Systems -- References -- 5 Biosensor Prospects: Quo Vadis? (Conclusion) -- References -- Appendix A Enzyme Kinetics -- Appendix B Inhibition Kinetics -- References -- Index