Synthesis of dl-cis- and (4R,5R)-trans-7-[2,2-dimethyl-4-(phenylsulfonyl)aminomethyl-1,3-dioxolan-5-yl]-5(Z)-heptenoic acid analogues as platelet thromboxane A2 receptor antagonsits

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Bibliographic Details
Published inEuropean journal of medicinal chemistry Vol. 30; no. 4; pp. 321 - 326
Main Authors KOMIOTIS, D, PANANOOKOOLN, S, ZAW, K, DIETER, J. P, LE BRETON, G. C, VENTON, D. L
Format Journal Article
LanguageEnglish
Published Oxford Elsevier 1995
Subjects
Biological and medical sciences
Medical sciences
Miscellaneous
Neuropharmacology
Neurotransmitters. Neurotransmission. Receptors
Pharmacology. Drug treatments
Human
Sulfonamide
Thromboxane A2
Oxygen heterocycle
In vitro
Biological activity
Antiplatelet agent
Isomer
Dioxolane derivatives
Acetal
Platelet
Carboxylic acid
Antagonist
Chemical synthesis
Biological receptor
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Author KOMIOTIS, D
LE BRETON, G. C
ZAW, K
DIETER, J. P
PANANOOKOOLN, S
VENTON, D. L
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  organization: Univ. Illinois Chicago, dep. medicinal chemistry pharmacognosy, United States
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  organization: Univ. Illinois Chicago, dep. medicinal chemistry pharmacognosy, United States
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  organization: Univ. Illinois Chicago, dep. pharmacology, Chicago IL 60612, United States
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  givenname: D. L
  surname: VENTON
  fullname: VENTON, D. L
  organization: Univ. Illinois Chicago, dep. medicinal chemistry pharmacognosy, United States
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Keywords Human
Sulfonamide
Thromboxane A2
Oxygen heterocycle
In vitro
Biological activity
Antiplatelet agent
Isomer
Dioxolane derivatives
Acetal
Platelet
Carboxylic acid
Antagonist
Chemical synthesis
Biological receptor
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StartPage 321
SubjectTerms Biological and medical sciences
Medical sciences
Miscellaneous
Neuropharmacology
Neurotransmitters. Neurotransmission. Receptors
Pharmacology. Drug treatments
Title Synthesis of dl-cis- and (4R,5R)-trans-7-[2,2-dimethyl-4-(phenylsulfonyl)aminomethyl-1,3-dioxolan-5-yl]-5(Z)-heptenoic acid analogues as platelet thromboxane A2 receptor antagonsits
Volume 30
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