DNA-directed alkylating agents. VI: Synthesis and antitumor activity of DNA minor groove-targeted aniline Mustard analogues of pibenzimol (Hoechst 33258)

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Bibliographic Details
Published inJournal of medicinal chemistry Vol. 37; no. 25; pp. 4338 - 4345
Main Authors GRAVATT, G. L, BAGULEY, B. C, WILSON, W. R, DENNY, W. A
Format Journal Article
LanguageEnglish
Published Washington, DC American Chemical Society 1994
Subjects
Antineoplastic agents
Biological and medical sciences
General aspects
Medical sciences
Pharmacology. Drug treatments
Antineoplastic agent
Rodentia
P388-Leukemia
Cytotoxicity
Binding site
In vitro
In vivo
Vertebrata
Alkylating agent
Mammalia
Structure activity relation
Benzimidazole derivatives
Animal
DNA
Nitrogen mustard
Established cell line
Chemical synthesis
Hamster
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Author BAGULEY, B. C
WILSON, W. R
GRAVATT, G. L
DENNY, W. A
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  organization: Univ. Auckland school medicine, dep. pathology, cancer res. lab., Auckland, New Zealand
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  fullname: WILSON, W. R
  organization: Univ. Auckland school medicine, dep. pathology, cancer res. lab., Auckland, New Zealand
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  givenname: W. A
  surname: DENNY
  fullname: DENNY, W. A
  organization: Univ. Auckland school medicine, dep. pathology, cancer res. lab., Auckland, New Zealand
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Issue 25
Keywords Antineoplastic agent
Rodentia
P388-Leukemia
Cytotoxicity
Binding site
In vitro
In vivo
Vertebrata
Alkylating agent
Mammalia
Structure activity relation
Benzimidazole derivatives
Animal
DNA
Nitrogen mustard
Established cell line
Chemical synthesis
Hamster
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PublicationTitle Journal of medicinal chemistry
PublicationYear 1994
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StartPage 4338
SubjectTerms Antineoplastic agents
Biological and medical sciences
General aspects
Medical sciences
Pharmacology. Drug treatments
Title DNA-directed alkylating agents. VI: Synthesis and antitumor activity of DNA minor groove-targeted aniline Mustard analogues of pibenzimol (Hoechst 33258)
Volume 37
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