Future of antibody purification : Polyclonal and monoclonal antibody production, purification, process and product analytics
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Published in | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Vol. 848; no. 1; pp. 48 - 63 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Amsterdam
Elsevier Science
2007
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Subjects | |
Online Access | Get full text |
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Author | LOW, Duncan PUJAR, Narahari S O'LEARY, Rhona |
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Author_xml | – sequence: 1 givenname: Duncan surname: LOW fullname: LOW, Duncan organization: Amgen, Thousand Oaks, CA, United States – sequence: 2 givenname: Rhona surname: O'LEARY fullname: O'LEARY, Rhona organization: Early Stage Purification, Genentech, South San Francisco, CA, United States – sequence: 3 givenname: Narahari S surname: PUJAR fullname: PUJAR, Narahari S organization: Bioprocess R&D, Merck & Co., Inc, West Point, PA, United States |
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Keywords | Membrane chromatography PAT Manufacturing facilities Protein precipitation Centrifuging Industrial Centrifugation Clearance Alternatives to protein A Aqueous medium Manufacturing Monoclonal Disposable technology Depth filtration Disposable Purification Protein crystallization Viral clearance Chemical precipitation Antibody Crystallization Protein A Protein Chromatography Phase separation Membrane filtration Future Aqueous two-phase separation Large scale Pharmacokinetics |
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SubjectTerms | Analysis Analytical, structural and metabolic biochemistry Biological and medical sciences Fundamental and applied biological sciences. Psychology General pharmacology Medical sciences Pharmacology. Drug treatments |
Title | Future of antibody purification : Polyclonal and monoclonal antibody production, purification, process and product analytics |
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