2,6,8,9-Tetrasubstituted purines as new CDK1 inhibitors Recent advances in the design of kinase inhibitors as novel therapeutic agents
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| Published in | Bioorganic & medicinal chemistry letters Vol. 13; no. 18; pp. 2993 - 2996 |
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| Main Authors | , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Oxford
Elsevier
2003
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| Subjects | |
| Online Access | Get full text |
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| Author | MORAVEC, Jiri STRNAD, Miroslav HANUS, Jan KRYSTOF, Vladimir OTYEPKA, Michal KUZMA, Marek HAVLICEK, Libor MORAVCOVA, Daniela FUKSOVA, Kvetoslava LENOBEL, René |
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| Keywords | Antineoplastic agent Human Phosphorylation Purine derivatives Enzyme Nitrogen heterocycle Transferases Leukemia Active site Enzyme inhibitor Cytotoxicity In vitro Modeling Signal transduction Cell line Structure activity relation Protein kinase Molecular model Bicyclic compound Mammary gland Chemical synthesis |
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| Subtitle | Recent advances in the design of kinase inhibitors as novel therapeutic agents |
| Title | 2,6,8,9-Tetrasubstituted purines as new CDK1 inhibitors |
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