446TiPREVEAL: A phase I/II, open-label, multicenter, dose escalation and dose expansion study of NKTR-262 [TLR 7/8 agonist] plus NKTR-214 [CD122-biased agonist] with or without nivolumab (nivo) in patients (pts) with locally advanced or metastatic solid tumor malignancies
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Published in | Annals of oncology Vol. 29; no. suppl_8 |
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Main Authors | , , , , , , , , , , |
Format | Journal Article |
Language | English |
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Oxford University Press
01.10.2018
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Author | Marcondes, M Rubas, W Zalevsky, J Tagliaferri, M A Hoch, U D'Angelo, S P Kivimae, S Conley, A P Borazanci, E Diab, A Zhang, J |
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Author_xml | – sequence: 1 givenname: A surname: Diab fullname: Diab, A organization: Department of Medical Oncology, MD Anderson Cancer Center, Houston, TX, USA – sequence: 2 givenname: M surname: Marcondes fullname: Marcondes, M organization: Oncology Clinical Development, Nektar Therapeutics, San Francisco, CA, USA – sequence: 3 givenname: M A surname: Tagliaferri fullname: Tagliaferri, M A organization: Clinical Development, Nektar Therapeutics, San Francisco, CA, USA – sequence: 4 givenname: U surname: Hoch fullname: Hoch, U organization: Oncology, Nektar Therapeutics, San Francisco, CA, USA – sequence: 5 givenname: J surname: Zhang fullname: Zhang, J organization: Clinical Development, Nektar Therapeutics, San Francisco, CA, USA – sequence: 6 givenname: W surname: Rubas fullname: Rubas, W organization: Oncology, Nektar Therapeutics, San Francisco, CA, USA – sequence: 7 givenname: S surname: Kivimae fullname: Kivimae, S organization: Oncology, Nektar Therapeutics, San Francisco, CA, USA – sequence: 8 givenname: J surname: Zalevsky fullname: Zalevsky, J organization: Biology, Nektar Therapeutics, San Francisco, CA, USA – sequence: 9 givenname: A P surname: Conley fullname: Conley, A P organization: Department of Medical Oncology, MD Anderson Cancer Center, Houston, TX, USA – sequence: 10 givenname: E surname: Borazanci fullname: Borazanci, E organization: Oncology, Honor Health/TGen, Scottsdale, AZ, USA – sequence: 11 givenname: S P surname: D'Angelo fullname: D'Angelo, S P organization: Medical Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA |
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Copyright | The Author(s) 2018. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissions@oup.com. 2018 |
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DOI | 10.1093/annonc/mdy279.433 |
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Title | 446TiPREVEAL: A phase I/II, open-label, multicenter, dose escalation and dose expansion study of NKTR-262 [TLR 7/8 agonist] plus NKTR-214 [CD122-biased agonist] with or without nivolumab (nivo) in patients (pts) with locally advanced or metastatic solid tumor malignancies |
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