How microscopic epistasis and clonal interference shape the fitness trajectory in a spin glass model of microbial long-term evolution

The adaptive dynamics of evolving microbial populations takes place on a complex fitness landscape generated by epistatic interactions. The population generically consists of multiple competing strains, a phenomenon known as clonal interference. Microscopic epistasis and clonal interference are cent...

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Bibliographic Details
Published ineLife Vol. 13
Main Authors Boffi, Nicholas M., Guo, Yipei, Rycroft, Chris H., Amir, Ariel
Format Journal Article
LanguageEnglish
Published United States eLife Sciences Publications, Ltd 20.02.2024
Subjects
BASIC BIOLOGICAL SCIENCES
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