Trocylation of 3-quinuclidinol, a key marker for the chemical warfare agent 3-quinuclidinyl benzilate, for its enhanced detection at low levels in complex soil matrices by electron ionization gas chromatography–mass spectrometry

• Published in: Rapid communications in mass spectrometry Vol. 35; no. 15
• Main Authors: Valdez, Carlos A., Leif, Roald N., Vu, Alexander K., Salazar, Edmund P.
• Format: Journal Article
• Language: English
• Published: United States Wiley 05.05.2021
• Subjects: INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Detection of 3-quinuclidinol (3Q), a marker for the chemical warfare agent 3-quinuclidinyl benzilate, is very difficult by gas chromatography–mass spectrometry (GC/MS), providing low, broad signals even when analyzed in isolated form. Therefore, a method that can convert 3Q into a substrate with enh...