Gene targets for engineering osmotolerance in Caldicellulosiruptor bescii

• Published in: Biotechnology for biofuels Vol. 13; no. 1
• Main Authors: Sander, Kyle B., Chung, Daehwan, Klingeman, Dawn M., Giannone, Richard J., Rodriguez, Jr., Miguel, Whitham, Jason, Hettich, Robert L., Davison, Brian H., Westpheling, Janet, Brown, Steven D.
• Format: Journal Article
• Language: English
• Published: Netherlands Springer Science + Business Media 13.03.2020
• Subjects: BASIC BIOLOGICAL SCIENCES; Caldicellulosiruptor bescii; dnaK; fapR; Fatty acid biosynthesis; fruR/cra; Osmotolerance

Abstract Background Caldicellulosiruptor bescii , a promising biocatalyst being developed for use in consolidated bioprocessing of lignocellulosic materials to ethanol, grows poorly and has reduced conversion at elevated medium osmolarities. Increasing tolerance to elevated fermentation osmolarities...