잠재적 치료 절제술이 가능했던 4기 위암 환자의 위절제술 후 성적-AJCC/UICC 분류(1997)를 기준으로

• Published in: Annals of surgical treatment and research pp. 383 - 389
• Main Authors: 정인목, 서준석, 김영철, 허승철, 안영준, 정중기
• Format: Journal Article
• Language: Korean
• Published: 대한외과학회 01.05.2003
• Subjects: 일반외과학
• ISSN: 2288-6575; 2288-6796

Purpose: The prognosis after potentially curative resection for stage IV gastric cancer, according to the 5th edition of AJCC/UICC classification, is poorly understood. The aim of this study was to evaluate the feasibility of the curative resection in patients with stage IV gastric cancer, which were considered potentially curable cases. Methods: From November 1991 to June 1996, 91 patients were confirmed as having stage IV gastric cancer at Seoul Boramae Municipal Hospital. Of these 91 patients, 30 who were potentially curative resected including at least D2 type lymph node dissections were reviewed retrospectively. The average numbers of totally dissected and positive lymph nodes were 43.0 (range: 26～74) and 23.1 (range: 2～47), respectively. Results: The overall 1-, 2-, and 5-year survival rates of patients were 60.0%, 36.7%, 13.3%, respectively. In comparison with stage IIIb (N=20), no significant difference in survival rate was observed (P=0.1178). In univariate analysis, we found that the presence of a recurrence (P=0.0121) and a P (positive lymph nodes)/R (total dissected lymph nodes) ＞0.6 were correlated with poor survival rates. Long- survivors (N=12, more than 24 months postoperatively) had a tendency to be younger, less recurrent (P=0.017) and less involvement of histological perineural invasion (P=0.028). Conclusion: The results of the present study indicate that stage IV patients without distant metastasis may indeed be cured by potentially curative surgery. (J Korean Surg Soc 2003;64:383-389) KCI Citation Count: 1