전립선 재생검 방법: 초음파 또는 자기공명영상 유도하에 따른 생검 결과와 수술 후 성적 비교

• Published in: Journal of Urologic Oncology, 15(2) pp. 72 - 78
• Main Authors: 정현우, 송완, 유재호, 강민용, 전황균, 정병창, 서성일, 전성수, 최한용, 김찬교, 박병관, 이현무
• Format: Journal Article
• Language: Korean
• Published: 대한비뇨기종양학회 01.08.2017
• Subjects: 비뇨기과학
• ISSN: 2951-603X; 2982-7043
• DOI: 10.22465/kjuo.2017.15.2.72

Purpose: We compared biopsy results and surgical outcomes of magnetic resonance imaging (MRI)-guided biopsy with transrectal ultrasonography (TRUS)-guided biopsy to demonstrate efficacy of MRI-guided biopsy on previous biopsy negative patients. Materials and Methods: We retrospectively reviewed data of 120 patients who were categorized into MRI-guided biopsy groups (n=20) and TRUS-guided biopsy groups (n=100). All patients were diagnosed with prostate cancer (PCa) and had undergone radical prostatectomy (RP) after MRI-guided or TRUS-guided repeat biopsy between January 2010 and March 2016. Detection rate of significant cancer and Gleason score upgrading and downgrading were examined, in addition to biopsy results and subsequent RP outcomes. Results: Median values for prostate-specific antigen level of the TRUS-guided biopsy group and the MRI-guided biopsy group were 6.67 and 5.86 ng/mL (p=0.303), respectively. Median prostate volume of each group (34.1 mL vs. 23.5 mL, p=0.007), number of positive cores (2.0 vs. 3.0, p=0.001) and maximum cancer/core rate (30.0% vs. 60.0%, p＜0.001) were statistically different. Positive core rates of each group were 21.9% and 87.1%, respectively. Pathologic T stage was the only variable that showed difference in surgical outcomes (p=0.002). Most of PCa was confirmed as clinically significant PCa after RP in MRI-guided biopsy group (95%). Conclusions: MRI-guided biopsy showed higher positive core rate and detection rate of clinically significant PCa than TRUS-guided biopsy in repeat biopsy setting. Prospective multicenter large-scale study and accumulation of data is expected to further define superiority of the MRI-guided biopsy. KCI Citation Count: 0