NF-κB Activation in T Helper 17 Cell Differentiation
CD28/T cell receptor ligation activates the NF-κB signaling cascade during CD4 T cell activation. NF-κB activation is required for cytokine gene expression and activated T cell survival and proliferation. Recently, many reports showed that NF-κB activation is also involved in T helper (Th) cell diff...
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| Published in | Immune network pp. 14 - 20 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
대한면역학회
01.02.2014
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1598-2629 2092-6685 |
| DOI | 10.41110/in.2014.14.1.14 |
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| Abstract | CD28/T cell receptor ligation activates the NF-κB signaling cascade during CD4 T cell activation. NF-κB activation is required for cytokine gene expression and activated T cell survival and proliferation. Recently, many reports showed that NF-κB activation is also involved in T helper (Th) cell differentiation including Th17 cell differentiation. In this review, we discuss the current literature on NF-κB activation pathway and its effect on Th17 cell differentiation. KCI Citation Count: 0 |
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| AbstractList | CD28/T cell receptor ligation activates the NF-κB signaling cascade during CD4 T cell activation. NF-κB activation is required for cytokine gene expression and activated T cell survival and proliferation. Recently, many reports showed that NF-κB activation is also involved in T helper (Th) cell differentiation including Th17 cell differentiation. In this review, we discuss the current literature on NF-κB activation pathway and its effect on Th17 cell differentiation. KCI Citation Count: 0 |
| Author | 조가비 박상헌 박성규 |
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| Snippet | CD28/T cell receptor ligation activates the NF-κB signaling cascade during CD4 T cell activation. NF-κB activation is required for cytokine gene expression and... |
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| Title | NF-κB Activation in T Helper 17 Cell Differentiation |
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