Transactivation of bad by vorinostat-induced acetylated p53 enhances doxorubicin-induced cytotoxicity in cervical cancer cells

• Published in: Experimental & molecular medicine pp. 1 - 8
• Main Authors: 이숙정, 황성욱, 노은주, 김동욱, 남미영, 김종혁, 남주현, 허광래
• Format: Journal Article
• Language: English
• Published: 생화학분자생물학회 01.02.2014
• Subjects: 생화학
• ISSN: 1226-3613; 2092-6413

Vorinostat (VOR) has been reported to enhance the cytotoxic effects of doxorubicin (DOX) with fewer side effects because of the lower DOX dosage in breast cancer cells. In this study, we investigated the novel mechanism underlying the synergistic cytotoxic effects of VOR and DOX co-treatment in cerv...