The Closed-Loop Neural Interface Available Simultaneously Recording and Stimulation Using Fast Convergence Stimulation Artifact Removal

The closed-loop neural interface is an actively researched field with broad applications. However, it has a serious issue in that stimulation itself makes huge artifacts (~mV) in the recording system saturating the amplifier, contaminating bio-signal (~ 50 V) and the post-analysis during a disturbed...

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Bibliographic Details
Published inIDEC Journal of Integrated Circuits and Systems, 10(3) pp. 32 - 37
Main Authors 성근창, 조재욱, 정희영, 김철
Format Journal Article
LanguageEnglish
Published 반도체설계교육센터 01.07.2024
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ISSN2384-2113
DOI10.23075/jicas.2024.10.3.006

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Summary:The closed-loop neural interface is an actively researched field with broad applications. However, it has a serious issue in that stimulation itself makes huge artifacts (~mV) in the recording system saturating the amplifier, contaminating bio-signal (~ 50 V) and the post-analysis during a disturbed period. Several stimulation artifact removal (SAR) techniques were presented but have trade-offs between conversion time and algorithm accuracy. Here, we suggested a closed-loop neural interface with a fast convergence SAR algorithm while sustaining adequate removal accuracy. The amplifier-free ADC-direct 2nd-order continuous delta-sigma modulator recording stage is adopted to provide ~15 Vrms input-referred integrated noise from 5Hz to 5kHz which is adequate to record bio-signal. Also, it succeeds in recording ~10mV signals about the size of the stimulation artifact. The fast-convergence SAR module provides stable accuracy under the versatile recording environment. The chip is designed using the TSMC 65-nm CMOS process. The chip is composed of 18 input channels, 2 SAR blocks, one stimulation channel, and 2 CIC filters for down-sampling. The entire chip area is 1mm2. KCI Citation Count: 0
ISSN:2384-2113
DOI:10.23075/jicas.2024.10.3.006