2C-08 Human and Mouse Induced Pluripotent Stem Cells Are Differentially Reprogrammed in response to Kinase Inhibitors

Conventional human induced pluripotent stem cells (hiPSCs), reprogrammed from somatic cells by induced expression of Oct4, Sox2, Klf4 and c-Myc (OSKM), are phenotypically different from mouse embryonic stem cells (ESCs). In mouse, culture in N2B27 serum-free 2i media (MEK and GSK3 inhibitors; PD0325...

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Bibliographic Details
Published inGenes & Genetic Systems Vol. 86; no. 6; p. 424
Main Authors HIRANO Kunio, NAGATA Shogo, YAMAGUCHI Shinpei, NAKAGAWA Masato, OKITA Keisuke, KOTERA Hidetoshi, AINSCOUGH Justin, TADA Takashi
Format Journal Article
LanguageJapanese
Published The Genetics Society of Japan 2011
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