Th17 Cell and Inflammatory Infiltrate Interactions in Cutaneous Leishmaniasis: Unraveling Immunopathogenic Mechanisms

• Published in: Immune network Vol. 24; no. 2; pp. 14.1 - 14.26
• Main Authors: Abraham U. Morales-Primo, Ingeborg Becker, Claudia Patricia Pedraza-Zamora, Jaime Zamora-Chimal
• Format: Journal Article
• Language: Korean
• Published: 2024
• Subjects: Cutaneous leishmaniasis; Immune response; Immunomodulation; Th17 cells; Host-pathogen interactions

The inflammatory response during cutaneous leishmaniasis (CL) involves immune and non-immune cell cooperation to contain and eliminate Leishmania parasites. The orchestration of these responses is coordinated primarily by CD4+ T cells; however, the disease outcome depends on the Th cell predominant...