Hydroalcoholic Extract of Scrophularia Striata Attenuates Hypertrophic Scar, Suppresses Collagen Synthesis, and Stimulates MMP2 and 9 Gene Expression in Rabbit Ear Model

• Published in: Journal of pharmacopuncture Vol. 25; no. 3; pp. 258 - 267
• Main Authors: Zarei, Hatam, Tamri, Pari, Asl, Sara Soleimani, Soleimani, Meysam, Moradkhani, Shirin
• Format: Journal Article
• Language: Korean
• Published: 2022
• Subjects: mmp2; epidermal thickness index; hypertrophic scar; scrophularia striata; scar elevation index; mmp9

Objectives: Hypertrophic scars (HSs) are caused by abnormal wound healing. To date, no standard treatment has been made available for HSs. Scrophularia striata has been reported to accelerate wound healing and has the potential to prevent HS formation. In this study, we investigated the anti-scarrin...