Tobacco Smoking Could Accentuate Epithelial-Mesenchymal Transition and Th2-Type Response in Patients With Chronic Rhinosinusitis With Nasal Polyps

• Published in: Immune network Vol. 22; no. 4; pp. 35.1 - 35.16
• Main Authors: Ki-Il Lee, Younghwan Han, Jae-Sung Ryu, Seung Min In, Jong-Yeup Kim, Joong Su Park, Jong-Seok Kim, Juhye Kim, Jubin Youn, Seok-Rae Park
• Format: Journal Article
• Language: Korean
• Published: 2022
• Subjects: Epithelial-mesenchymal transition; Chronic rhinosinusitis with nasal polyps; IgE; Tobacco smoking; Epithelial-derived cytokines

Tobacco smoking (TS) has been known as one of the most potent risk factors for airway inflammatory diseases. However, there has been a paucity of information regarding the immunologic alteration mediated by TS in patients with chronic rhinosinusitis with nasal polyps (CRSwNP). To identify the effect...