Single-Molecule Imaging Reveals the Mechanism Underlying Histone Loading of Schizosaccharomyces pombe AAA+ ATPase Abo1

• Published in: Molecules and cells Vol. 44; no. 2; pp. 79 - 87
• Main Authors: Kang, Yujin, Cho, Carol, Lee, Kyung Suk, Song, Ji-Joon, Lee, Ja Yil
• Format: Journal Article
• Language: Korean
• Published: 2021
• Subjects: single-molecule photobleaching; histone loading; bromodomain-containing AAA+ ATPase; DNA curtain

Chromatin dynamics is essential for maintaining genomic integrity and regulating gene expression. Conserved bromodomain-containing AAA+ ATPases play important roles in nucleosome organization as histone chaperones. Recently, the high-resolution cryo-electron microscopy structures of Schizosaccharomy...