Inhibitory Effect of Retinoids on Alkaline Phosphatase Isoenzymes Activity in Human Serum

• Published in: Journal of experimental & biomedical sciences Vol. 23; no. 3; pp. 230 - 237
• Main Authors: Kim, Seung Hee, Moon, Ki-Young
• Format: Journal Article
• Language: Korean
• Published: 2017
• Subjects: Tissue-specific alkaline phosphatase; All-trans retinoic acid; 13-cis retinoic acid; Human serum alkaline phosphatase isoenzymes

Changes in the activity of alkaline phosphatase (ALP) isoenzymes and isoforms in human serum have a major diagnostic value, therefore the regulation of ALP activities is a valuable target for therapeutic interventions. To assess the pharmacological activity of retinoids, i.e., all-trans retinoic aci...