Screening and Characterization of a Novel RNA Aptamer That Specifically Binds to Human Prostatic Acid Phosphatase and Human Prostate Cancer Cells

• Published in: Molecules and cells Vol. 38; no. 2; pp. 171 - 179
• Main Authors: Kong, Hoon Young, Byun, Jonghoe
• Format: Journal Article
• Language: Korean
• Published: 2015
• Subjects: RNA aptamer; prostate cancer; prostatic acid phosphatase; biomarker

Prostatic acid phosphatase (PAP) expression increases proportionally with prostate cancer progression, making it useful in prognosticating intermediate to high-risk prostate cancers. A novel ligand that can specifically bind to PAP would be very helpful for guiding prostate cancer therapy. RNA aptam...