Methylation of SFRPs and APC Genes in Ovarian Cancer Infected with High Risk Human Papillomavirus

Background: Secreted frizzled-related protein (SFRP) genes, new tumor suppressor genes, are negative regulators of the Wnt pathway whose alteration is associated with various tumors. In ovarian cancer, SFRPs genes promoter methylation can lead to gene inactivation. This study investigated mechanisms...

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Bibliographic Details
Published inAsian Pacific journal of cancer prevention : APJCP Vol. 15; no. 6; pp. 2719 - 2725
Main Authors Al-Shabanah, Othman Abdulla, Hafez, Mohamed Mahmoud, Hassan, Zeinab Korany, Sayed-Ahmed, Mohamed Mohamed, Abozeed, Waleed Nabeel, Alsheikh, Abdulmalik, Al-Rejaie, Salem Saleh
Format Journal Article
LanguageKorean
Published 2014
Subjects
SFRPs and APC genes
Wnt pathway
DNA methylation
MSP
Ovarian cancer
HPV
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