Tim-3 Expression by Peripheral Natural Killer Cells and Natural Killer T Cells Increases in Patients with Lung Cancer - Reduction after Surgical Resection

• Published in: Asian Pacific journal of cancer prevention : APJCP Vol. 15; no. 22; pp. 9945 - 9948
• Main Authors: Xu, Li-Yun, Chen, Dong-Dong, He, Jian-Ying, Lu, Chang-Chang, Liu, Xiao-Guang, Le, Han-Bo, Wang, Chao-Ye, Zhang, Yong-Kui
• Format: Journal Article
• Language: Korean
• Published: 2014
• Subjects: T cell immunoglobulin; natural killer cells; Lung cancer; mucin domain 3; flow cytometry

Background: The purpose of this study was to investigate Tim-3 expression on peripheral CD3-CD56+ natural killer (NK) cells and CD3+CD56+ natural killer T (NKT) cells in lung cancer patients. Materials and Methods: We analyzed Tim-3+CD3-CD56+ cells, Tim-3+CD3-$CD56^{dim}$ cells, Tim-3+CD3-$CD56^{bri...