Alternative Mechanism of Aspirin in Anti-Thrombotic Therapy: Inhibition of Thrombin Activatable Fibrinolysis Inhibitor

The use of aspirin is widely recommended for the prevention of heart attacks owing to its ability to inhibit platelet activation by irreversibly blocking cyclooxygenase 1. However, aspirin also affects the fibrinolytic and hemostatic pathways by mechanisms that are not well understood, causing sever...

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Bibliographic Details
Published inBulletin of the Korean Chemical Society Vol. 33; no. 9; pp. 3048 - 3054
Main Authors An, Seong-Soo A, Greenfield, Robert S
Format Journal Article
LanguageKorean
Published 2012
Subjects
Thrombin activatable fibrinolysis inhibitor (TAFI)
Aspirin
Fibrinolysis
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