Dual Inhibitions of Lemon Balm (Melissa officinalis) Ethanolic Extract on Melanogenesis in B16-F1 Murine Melanocytes: Inhibition of Tyrosinase Activity and Its Gene Expression

• Published in: Food science and biotechnology Vol. 20; no. 4; pp. 1051 - 1059
• Main Authors: Jun, Hee-Jin, Roh, Mi-Ran, Kim, Hae-Won, Houng, Soung-Jin, Cho, Bo-Ram, Yun, Eun-Joo, Hossain, Md.A, Lee, Ho-Joung, Kim, Kyoung-Heon, Lee, Sung-Joon
• Format: Journal Article
• Language: Korean
• Published: 2011
• Subjects: hypopigmentation; lemon balm (Melissa officinalis); UV-irradiation; tyrosinase

The effects of wild type and UV-irradiated lemon balm (Melissa officinalis) ethanolic extracts (MOE and UMOE) on melanogenesis in vitro were examined. UMOE showed potent antioxidant activity and significantly inhibited the mushroom and melanocyte tyrosinase activity, and lowered cellular melanin con...