Polymorphisms of methylenetetrahydrofolate reductase are not a risk factor for Kawasaki disease in the Korean population

• Published in: Korean journal of pediatrics Vol. 54; no. 8; pp. 335 - 339
• Main Authors: Yoon, Kyung-Lim, Ko, Jin-Hee, Shim, Kye-Shik, Han, Mi-Young, Cha, Sung-Ho, Kim, Su-Kang, Jung, Joo-Ho
• Format: Journal Article
• Language: Korean
• Published: 2011
• Subjects: Kawasaki disease; Coronary artery lesion; Hyperhomocysteinemia; Methylenetetrahydrofolate reductase; Polymorphism

Purpose: Hyperhomocysteinemia is known as a risk factor for atherosclerosis. Preclinical arteriosclerosis is noted and premature atherosclerosis is known to be accelerated in Kawasaki disease (KD) patients. Genetic polymorphisms in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene result in...