Syntheses of Resveratrol and its Hydroxylated Derivatives as Radical Scavenger and Tyrosinase Inhibitor

• Published in: Bulletin of the Korean Chemical Society Vol. 31; no. 4; pp. 971 - 975
• Main Authors: Lee, Hyun-Suck, Lee, Byung-Won, Kim, Mi-Ran, Jun, Jong-Gab
• Format: Journal Article
• Language: Korean
• Published: 2010
• Subjects: ABTS radical; Resveratrol; Tyrosinase inhibitor; Piceatannol; Stilbene

Eight hydroxylated stilbene derivatives including resveratrol, desoxyrhapontigenin and piceatannol as potential radical scavenger and tyrosinase inhibitor are synthesized using optimized Wittig-Horner reaction for excellent trans-selectivity in good yields. Antioxidant activity was tested against AB...