A Thermodynamic Investigation into the Stabilization of Poly(dA).[poly(dT)] 2 Triple Helical DNA by Various Divalent Metal Ions

• Published in: Bulletin of the Korean Chemical Society Vol. 30; no. 11; pp. 2691 - 2696
• Main Authors: Choi, Byung-Hoon, Yeo, Ga-Young, Jung, Jin-Ah, Lee, Bae-Wook, Han, Sung-Wook, Cho, Tae-Sub
• Format: Journal Article
• Language: Korean
• Published: 2009
• Subjects: Thermodynamics; Enthalpy; Triplex DNA; Entropy; Divalent ions

Effects of representative group II and transition metal ions on the stability of the $poly(dA){\cdot}[poly(dT)]_2$ triplex were investigated by the van’t Hoff plot constructed from a thermal melting curve. The transition, $poly(dA){\cdot}[poly(dT)]_2\;{\rightarrow}\;poly(dA){\cdot}poly(dT)\;+\;poly(...