Studies on the Small Body Size Mouse Developed by Mutagen N-Ethyl-N-nitrosourea

• Published in: Toxicological research (Seoul) Vol. 24; no. 1; pp. 69 - 78
• Main Authors: Zhang, Qian-Kun, Cho, Kyu-Hyuk, Cho, Jae-Woo, Cha, Dal-Sun, Park, Han-Jin, Yoon, Seok-Joo, Zhang, ShouFa, Song, Chang-Woo
• Format: Journal Article
• Language: Korean
• Published: 2008
• Subjects: Small body size mice; Body weight; Bone mineral density; Linkage analysis

Mutant mouse which show dwarfism has been developed by N-ethyl-N-nitrosourea (ENU) mutagenesis using BALB/c mice. The mutant mouse was inherited as autosomal recessive trait and named Small Body Size (SBS) mouse. The phenotype of SBS mouse was not apparent at birth, but it was possible to distinguis...