소아에서 발생한 위장관 간질 종양 1예

Gastrointestinal stromal tumors (GISTs) are the most common primary mesenchymal tumors of the digestive tract. They have been commonly observed in adults but have been rarely described in children. They arise typically from the intestinal wall and rarely in the mesentery, omentum, or retroperitoneum...

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Published in대한소아소화기영양학회지 Vol. 10; no. 1; pp. 71 - 75
Main Authors 윤경빈, 김재영, 유재홍, 설지영, 강대영, Yun, Kyung-Bin, Kim, Jae-Young, Ryu, Jae-Hong, Sul, Ji-Young, Kang, Dae-Young
Format Journal Article
LanguageKorean
Published 2007
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Abstract Gastrointestinal stromal tumors (GISTs) are the most common primary mesenchymal tumors of the digestive tract. They have been commonly observed in adults but have been rarely described in children. They arise typically from the intestinal wall and rarely in the mesentery, omentum, or retroperitoneum. GISTs originate from the interstitial cell of Cajal and are characterized by overexpression of the receptor tyrosine kinase c-kit. Up to 94% of these tumors express the CD117 on immunohistochemical stain. Surgery is the main modality of treatment for primary resectable GIST. Completely resectable GIST with low risk has excellent prognosis after primary surgical intervention, with over 90% of the 5-year survival. We report a case of 10-year-old girl presenting with an upper gastrointestinal bleeding caused by gastrointestinal stromal tumor. 저자들은 2년 전부터 식사 후에 주로 나타나는 간헐적인 상복부 복통이 있어오다가 한 차례 흑혈변을 보여인근 병원에서 시행한 혈액검사에서 빈혈을 보여 전원된 10세 여아에서 소아에서는 발생이 드물다고 알려진 위에서 발생한 GIST 1예를 경험하였기에 문헌고찰과 함께 보고한다.
AbstractList Gastrointestinal stromal tumors (GISTs) are the most common primary mesenchymal tumors of the digestive tract. They have been commonly observed in adults but have been rarely described in children. They arise typically from the intestinal wall and rarely in the mesentery, omentum, or retroperitoneum. GISTs originate from the interstitial cell of Cajal and are characterized by overexpression of the receptor tyrosine kinase c-kit. Up to 94% of these tumors express the CD117 on immunohistochemical stain. Surgery is the main modality of treatment for primary resectable GIST. Completely resectable GIST with low risk has excellent prognosis after primary surgical intervention, with over 90% of the 5-year survival. We report a case of 10-year-old girl presenting with an upper gastrointestinal bleeding caused by gastrointestinal stromal tumor. 저자들은 2년 전부터 식사 후에 주로 나타나는 간헐적인 상복부 복통이 있어오다가 한 차례 흑혈변을 보여인근 병원에서 시행한 혈액검사에서 빈혈을 보여 전원된 10세 여아에서 소아에서는 발생이 드물다고 알려진 위에서 발생한 GIST 1예를 경험하였기에 문헌고찰과 함께 보고한다.
Author 김재영
유재홍
Sul, Ji-Young
강대영
Ryu, Jae-Hong
설지영
Yun, Kyung-Bin
Kim, Jae-Young
윤경빈
Kang, Dae-Young
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  fullname: 강대영
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  fullname: Yun, Kyung-Bin
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  fullname: Kim, Jae-Young
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  fullname: Ryu, Jae-Hong
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  fullname: Sul, Ji-Young
– sequence: 10
  fullname: Kang, Dae-Young
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Keywords Receptor tyrosine kinase c-kit
Interstitial cell of Cajal
CD117
Immunohistochemical stain
Gastrointestinal stromal tumors (GISTs)
Language Korean
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Snippet Gastrointestinal stromal tumors (GISTs) are the most common primary mesenchymal tumors of the digestive tract. They have been commonly observed in adults but...
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Title 소아에서 발생한 위장관 간질 종양 1예
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