Clinically Useful Diagnostic Tool of Contrast Enhanced Ultrasonography for Focal Liver Masses: Comparison to Computed Tomography and Magnetic Resonance Imaging
Background/Aims: To evaluate the diagnostic value of con-trast (SonoVue®) enhancement ultrasonography (CEUS) and to compare this method with computed tomography (CT) and magnetic resonance imaging (MRI) in evaluating liver mass-es. Methods: CEUS (n=50), CT (n=47), and MRI (n=43) were performed on 50...
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Published in | Gut and liver Vol. 8; no. 3; pp. 292 - 297 |
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Main Authors | , , , , , , , , , , , , |
Format | Journal Article |
Language | Korean |
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대한간학회
30.05.2014
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Abstract | Background/Aims: To evaluate the diagnostic value of con-trast (SonoVue®) enhancement ultrasonography (CEUS) and to compare this method with computed tomography (CT) and magnetic resonance imaging (MRI) in evaluating liver mass-es. Methods: CEUS (n=50), CT (n=47), and MRI (n=43) were performed on 50 liver masses in 48 patients for baseline mass characterization. The most likely impression for each modality and the final diagnosis, based on the combined biopsy results (n=14), angiography findings (n=36), and clini-cal course, were determined. The diagnostic value of CEUS was compared to those of CT and MRI. Results: The final di-agnosis of the masses was hepatocellular carcinoma (n=43), hemangioma (n=3), benign adenoma (n=2), eosinophilic abscess (n=1), and liver metastasis (n=1). The overall diag-nostic agreement with the final diagnosis was substantial for CEUS, CT, and MRI, with κ values of 0.621, 0.763, and 0.784, respectively. The sensitivity, specificity, and accuracy were 83.3%, 87.5%, and 84.0%, respectively, for CEUS; 95.0%, 87.5%, and 93.8%, respectively, for CT; and 94.6%, 83.3%, and 93.0%, respectively for MRI. After excluding the lesions with poor acoustic sonographic windows, the sensitivity, specificity, and accuracy for CEUS were 94.6%, 87.5%, and 93.3%, respectively, with a κ value of 0.765. Conclusions: If an appropriate acoustic window is available, CEUS is compa-rable to CT and MRI for the diagnosis of liver masses.(Gut Liver 2014;8:292-297) |
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AbstractList | Background/Aims: To evaluate the diagnostic value of con-trast (SonoVue®) enhancement ultrasonography (CEUS) and to compare this method with computed tomography (CT) and magnetic resonance imaging (MRI) in evaluating liver mass-es. Methods: CEUS (n=50), CT (n=47), and MRI (n=43) were performed on 50 liver masses in 48 patients for baseline mass characterization. The most likely impression for each modality and the final diagnosis, based on the combined biopsy results (n=14), angiography findings (n=36), and clini-cal course, were determined. The diagnostic value of CEUS was compared to those of CT and MRI. Results: The final di-agnosis of the masses was hepatocellular carcinoma (n=43), hemangioma (n=3), benign adenoma (n=2), eosinophilic abscess (n=1), and liver metastasis (n=1). The overall diag-nostic agreement with the final diagnosis was substantial for CEUS, CT, and MRI, with κ values of 0.621, 0.763, and 0.784, respectively. The sensitivity, specificity, and accuracy were 83.3%, 87.5%, and 84.0%, respectively, for CEUS; 95.0%, 87.5%, and 93.8%, respectively, for CT; and 94.6%, 83.3%, and 93.0%, respectively for MRI. After excluding the lesions with poor acoustic sonographic windows, the sensitivity, specificity, and accuracy for CEUS were 94.6%, 87.5%, and 93.3%, respectively, with a κ value of 0.765. Conclusions: If an appropriate acoustic window is available, CEUS is compa-rable to CT and MRI for the diagnosis of liver masses.(Gut Liver 2014;8:292-297) |
Author | Jin Nyoung Kim Woong Cheul Lee Kwang Yeun Shim Nam Seok Ham Jae Young Jang Ji Hye Kim Sang Woo Cha Sung Woo Ryu Eui Ju Park Soung Won Jeong Sae Hwan Lee Gene Hyun Bok Sang Gyune Kim |
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SubjectTerms | Contrast enhanced ultrasonography Liver masses |
Title | Clinically Useful Diagnostic Tool of Contrast Enhanced Ultrasonography for Focal Liver Masses: Comparison to Computed Tomography and Magnetic Resonance Imaging |
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