BMB Reports : Binding model for eriodictyol to Jun-N terminal kinase and its anti-inflammatory signaling pathway

• Published in: BMB reports Vol. 46; no. 12; pp. 594 - 599
• Main Authors: Eun Jung Lee, Ki Woong Jeong, Areum Shin, Bong Hwan Jin, Hum Nath Jnawali, Bong Hyun Jun, Jee Young Lee, Yong Seok Heo, Yang Mee Kim
• Format: Journal Article
• Language: Korean
• Published: 생화학분자생물학회 30.12.2013
• Subjects: Anti-inflammatory activity; Docking model; Eriodictyol; Flavonoid; STD-NMR

The anti-inflammatory activity of eriodictyol and its mode of action were investigated. Eriodictyol suppressed tumor necrosis factor (mTNF)-α, inducible nitric oxide synthase (miNOS), interleukin (mIL)-6, macrophage inflammatory protein (mMIP)-1, and mMIP-2 cytokine release in LPS-stimulated macroph...