Case Report : A Case of Primary Neuroendocrine Carcinoma of the Gallbladder Associated with Anomalous Union of the Pancreaticobiliary Duct

Primary neuroendocrine carcinoma of the gallbladder is extremely rare because normal gallbladder mucosa does not contain neuroendocrine cells. Neuroendocrine cells can be detected at sites of intestinal metaplasia induced by chronic inflammation, which may be the initial step in the development of n...

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Published inGut and liver Vol. 3; no. 3; pp. 231 - 234
Main Authors Kyoung Won Yoon, Chang Hwan Park, Wan Sik Lee, Young Eun Joo, Hyeun Soo Kim, Sung Kyu Choi, Jong Sun Rew, Jae Hyug Lee
Format Journal Article
LanguageKorean
Published 대한간학회 30.09.2009
Subjects
Anomalous union
Gallbladder
Neuroendocrine tumor
Pancreaticobiliary duct
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Abstract Primary neuroendocrine carcinoma of the gallbladder is extremely rare because normal gallbladder mucosa does not contain neuroendocrine cells. Neuroendocrine cells can be detected at sites of intestinal metaplasia induced by chronic inflammation, which may be the initial step in the development of neuroendocrine tumor of the gallbladder. Anomalous union of the pancreaticobiliary duct (AUPBD) is an uncommon congenital anomaly that is frequently associated with choledocholithiasis, cholangitis, pancreatitis, and cancer of the gallbladder or bile duct. In AUPBD, cancers of the gallbladder and bile duct can be induced by chronic inflammation. We report herein a case of large-cell neuroendocrine tumor of the gallbladder associated with AUPBD. (Gut and Liver 2009;3:231-234)
AbstractList Primary neuroendocrine carcinoma of the gallbladder is extremely rare because normal gallbladder mucosa does not contain neuroendocrine cells. Neuroendocrine cells can be detected at sites of intestinal metaplasia induced by chronic inflammation, which may be the initial step in the development of neuroendocrine tumor of the gallbladder. Anomalous union of the pancreaticobiliary duct (AUPBD) is an uncommon congenital anomaly that is frequently associated with choledocholithiasis, cholangitis, pancreatitis, and cancer of the gallbladder or bile duct. In AUPBD, cancers of the gallbladder and bile duct can be induced by chronic inflammation. We report herein a case of large-cell neuroendocrine tumor of the gallbladder associated with AUPBD. (Gut and Liver 2009;3:231-234)
Author Jae Hyug Lee
Sung Kyu Choi
Jong Sun Rew
Young Eun Joo
Kyoung Won Yoon
Wan Sik Lee
Chang Hwan Park
Hyeun Soo Kim
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Snippet Primary neuroendocrine carcinoma of the gallbladder is extremely rare because normal gallbladder mucosa does not contain neuroendocrine cells. Neuroendocrine...
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SubjectTerms Anomalous union
Gallbladder
Neuroendocrine tumor
Pancreaticobiliary duct
Title Case Report : A Case of Primary Neuroendocrine Carcinoma of the Gallbladder Associated with Anomalous Union of the Pancreaticobiliary Duct
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