Treatment and Prevention of Rat Glioblastma by Immunogenic C6 Cells Expressing Antisense Insulin-Like Growth Factor I RNA
Rat C6 glioma cells express insulin-like growth factor I (IGF-I) and form rapidly growing tumors in syngeneic animals. When transfected with an episome-based vector encoding antisense IGF-I complementary DNA, these cells lost tumorigenicity. Subcutaneous injection of IGF-I antisense-transfected C6 c...
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Published in | Science (American Association for the Advancement of Science) Vol. 259; no. 5091; pp. 94 - 97 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
American Society for the Advancement of Science
01.01.1993
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Subjects | |
Online Access | Get full text |
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