Physical Inactivity Is Associated with Lower Forced Expiratory Volume in 1 Second
Forced expiratory volume in 1 second (FEV1) is a strong risk factor for cardiovascular disease, stroke, lung cancer, and all-cause mortality. One possible explanation for this association is that FEV1 is a marker of other determinants of mortality risk, such as obesity and physical inactivity. In a...
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Published in | American journal of epidemiology Vol. 156; no. 2; pp. 139 - 147 |
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Main Authors | , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Oxford University Press
15.07.2002
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Subjects | |
Online Access | Get full text |
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Summary: | Forced expiratory volume in 1 second (FEV1) is a strong risk factor for cardiovascular disease, stroke, lung cancer, and all-cause mortality. One possible explanation for this association is that FEV1 is a marker of other determinants of mortality risk, such as obesity and physical inactivity. In a population-based cohort study of 12,283 men and women aged 45–74 years from the European Prospective Investigation into Cancer-Norfolk Study recruited in 1993–1997, the cross-sectional association between physical activity and FEV1 and that between physical activity and change in FEV1 were analyzed. Indices of physical activity, including participation in vigorous recreational activity, stair climbing, and television viewing, were assessed with a validated questionnaire designed to assess activity in the previous year. Television viewing was negatively associated with FEV1 in men and women (p < 0.001), whereas stair climbing and participation in vigorous leisure time activities were positively associated with FEV1 in men and women (p < 0.001). The associations remained after adjustment for known confounders, including age, height, vitamin C, and smoking. Climbing more stairs and participating in vigorous leisure-time activity predicted a slower rate in annual percent decline in FEV1 (p < 0.004 and p < 0.002, respectively). In conclusion, physical activity is associated with higher levels of FEV1, whereas television viewing is associated with lower levels. Am J Epidemiol 2002;156:139–47. |
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Bibliography: | Received for publication October 11, 2001; accepted for publication March 20, 2002. istex:0153744941E50D6285F0C04967FE02C3BED81974 ark:/67375/HXZ-N8K5SH82-C local:kwf021 |
ISSN: | 0002-9262 1476-6256 |
DOI: | 10.1093/aje/kwf021 |