Biodegradable polymers: production, properties and application in medicine

• Published in: Technologica acta (Tuzla. Online) Vol. 11; no. 1; p. 25
• Main Authors: Cipurković, Amira, Horozić, Emir, Đonlagić, Nusreta, Marić, Snježana, Saletović, Mirzeta, Ademović, Zahida
• Format: Journal Article
• Language: English
• Published: Tehnološki fakultet Tuzla 23.07.2018
• Subjects: poly-ε-coprolactone (PCL); polybutylene succinate (PBS); polyglycolic acid (PGA); polylactide acid (PLA)
• ISSN: 1840-0426; 2232-7568

Biodegradable polymers (biopolymers) represent materials of new generation with application in different areas of human activity. Their production has recently reached a commercial level. They can be divided according to the origin (natural and synthetic), according to the chemical composition, methods of obtaining, application etc. The use of biopolymers in medicine depends on their biocompatibility, mechanical resistance, and sorptive char-acteristics. Today, they are the most commonly used as implants in vascular and orthopedic surgery, for the production of materials such as catheters, products for gynaecology and haemodialysis, tooth reconstruction, etc. In pharmacy, they are used as a medicine matrix-carrier to allow controlled release of drug within the body. Within this review paper, the properties and methods of production of certain biopolymers such as polyglycolic acid (PGA), polylactide acid (PLA), poly-ε-coprolactone (PCL) and polybutylene succinate (PBS) will be described in detail, as well as their application in medicine and pharmacy.