Organophosphate Poisoning Management in a Primary Healthcare Facility in Nigeria: A Case Report

Background: Organophosphate poisoning causes a range of symptoms affecting multiple organ systems. Delayed presentation and diagnosis may be catastrophic and ultimately fatal. The population most at risk are young adults, and in our environment where health seeking behaviour does not favour early pr...

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Published inAsian Journal of Advanced Research and Reports Vol. 19; no. 9; pp. 1 - 5
Main Authors Erhiori, Akponah, Kohworho, Umukoro Emuesiri, Blessing, Elijah Oghenekparobor, Vincent-Junior, Igben Onoriode
Format Journal Article
LanguageEnglish
Published 28.08.2025
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Abstract Background: Organophosphate poisoning causes a range of symptoms affecting multiple organ systems. Delayed presentation and diagnosis may be catastrophic and ultimately fatal. The population most at risk are young adults, and in our environment where health seeking behaviour does not favour early presentation in the hospitals, management is challenging especially in primary health facilities with limited capacity to test and manage. Objective: The objective of this case report is to describe the presentation, investigation and management of a case of organophosphate poisoning in a primary health centre (PHC). Case Presentation: We report our experience in managing a 21 year old female patient who presented following ingestion of an organophosphate containing poison about 7 hours post incident. She was drowsy at presentation and history was given by her sister. She was stabilized, managed with atropine and fluids. Her general condition improved significantly over the first 24 hours and she was discharged on the 4th day post admission. A referral to a psychiatrist was made on discharge. We discuss relevant considerations of management of such poisonings, the clinical features, investigations and outcomes. We also discuss the limitations with management of these cases in our setting. Conclusion: Incidence of organophosphate poisoning is increasing and mortality rates are relatively high due to late presentation and delays in management. Furthermore, limitations in primary care centres with distant referral centres puts a demand on the primary care physician to institute all life saving and initial management before referral. The index case was managed as a case of organophosphate poisoning secondary to a suicide attempt with a favourable outcome and subsequent referral to a psychiatrist. A high index of suspicion is needed in an environment with a young population.
AbstractList Background: Organophosphate poisoning causes a range of symptoms affecting multiple organ systems. Delayed presentation and diagnosis may be catastrophic and ultimately fatal. The population most at risk are young adults, and in our environment where health seeking behaviour does not favour early presentation in the hospitals, management is challenging especially in primary health facilities with limited capacity to test and manage. Objective: The objective of this case report is to describe the presentation, investigation and management of a case of organophosphate poisoning in a primary health centre (PHC). Case Presentation: We report our experience in managing a 21 year old female patient who presented following ingestion of an organophosphate containing poison about 7 hours post incident. She was drowsy at presentation and history was given by her sister. She was stabilized, managed with atropine and fluids. Her general condition improved significantly over the first 24 hours and she was discharged on the 4th day post admission. A referral to a psychiatrist was made on discharge. We discuss relevant considerations of management of such poisonings, the clinical features, investigations and outcomes. We also discuss the limitations with management of these cases in our setting. Conclusion: Incidence of organophosphate poisoning is increasing and mortality rates are relatively high due to late presentation and delays in management. Furthermore, limitations in primary care centres with distant referral centres puts a demand on the primary care physician to institute all life saving and initial management before referral. The index case was managed as a case of organophosphate poisoning secondary to a suicide attempt with a favourable outcome and subsequent referral to a psychiatrist. A high index of suspicion is needed in an environment with a young population.
Author Kohworho, Umukoro Emuesiri
Vincent-Junior, Igben Onoriode
Erhiori, Akponah
Blessing, Elijah Oghenekparobor
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  surname: Erhiori
  fullname: Erhiori, Akponah
  organization: Department of Pharmacology and Therapeutics, Faculty of Basic Clinical Sciences, Delta, State University, Abraka, Nigeria, University Health Services, Delta State University, Abraka, Nigeria and Dpurity Hospital Abraka, Nigeria
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  givenname: Umukoro Emuesiri
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  organization: Department of Pharmacology and Therapeutics, Faculty of Basic Clinical Sciences, Delta, State University, Abraka, Nigeria and University Health Services, Delta State University, Abraka, Nigeria
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  givenname: Elijah Oghenekparobor
  surname: Blessing
  fullname: Blessing, Elijah Oghenekparobor
  organization: Department of Pharmacology and Therapeutics, Faculty of Basic Clinical Sciences, Delta, State University, Abraka, Nigeria and University Health Services, Delta State University, Abraka, Nigeria
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  givenname: Igben Onoriode
  surname: Vincent-Junior
  fullname: Vincent-Junior, Igben Onoriode
  organization: Department of Pharmacology and Therapeutics, Faculty of Basic Clinical Sciences, Delta, State University, Abraka, Nigeria and University Health Services, Delta State University, Abraka, Nigeria
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Snippet Background: Organophosphate poisoning causes a range of symptoms affecting multiple organ systems. Delayed presentation and diagnosis may be catastrophic and...
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Medical Imaging
Title Organophosphate Poisoning Management in a Primary Healthcare Facility in Nigeria: A Case Report
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