CD44S expression in breast carcinoma/ Meme karsinomunda CD44S ekspresyonu

The aim of our study is to compare the expression of CD44S with well known prognostic factors as a lymph node status and eostrogen, progesterone in breast carcinoma. The study was performed with the cell blocks of 40 patients with breast carcinoma. Six patients with benign lesions were used as contr...

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Published inTürk onkoloji dergisi Vol. 29; no. 1; p. 11
Main Authors Yoruker, Ebru Esin, Mutlu Guner, Sevcihan, Dolek Guler, Semra, Alatli, Fatma Canan
Format Journal Article
LanguageTurkish
Published KARE Publishing 01.03.2014
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Summary:The aim of our study is to compare the expression of CD44S with well known prognostic factors as a lymph node status and eostrogen, progesterone in breast carcinoma. The study was performed with the cell blocks of 40 patients with breast carcinoma. Six patients with benign lesions were used as control. Immunocytochemistry staining method was applied to the sections prepared from the cell blocks. Slides were evaluated and correlations between CD44S positivity and lymph node metastasis and other parameters. CD44 positivity were detected in 29 cases and 11 cases negative. All of the cases in the control group were positive for CD44S anitbody. No statistically significant correlations were established between CD44S expressions and other parameters. As a result of this study it is concluded that CD44S expression has no realtionship with lymph node metastasis, eostrogen and progesterone positivities in breast carcinoma.
ISSN:1300-7467
DOI:10.5505/tjoncol.2014.968