Ultrasensitive impedimetric mercury-thymine interaction and subsequent disintegration of multiple sandwich-structured DNA chains

• Published in: Mikrochimica acta (1966) Vol. 185; no. 12
• Main Authors: Gao, Feng, Zhang, Taoshun, Chu, Yaru, Wang, Qingxiang, Song, Juan, Qiu, Weiwei, Lin, Zhenyu
• Format: Journal Article
• Language: English
• Published: Springer 01.12.2018
• Subjects: DNA; Electric properties; Electrolytes; Pyrimidines; Sensors

An impedimetric method is described for ultrasensitive analysis of mercury(II). It is based on thymine-Hg(II)-thymine interaction which causes the disintegration of multiple-sandwich structured DNA chains. DNA strands were selected that are partially complementary to the T-rich Hg(II)-specific oligo...