Promoter polymorphism -119C/G in MYG1

• Published in: BMC medical genetics Vol. 11; pp. 56 - 111
• Main Authors: Philips, Mari-Anne, Kingo, Külli, Karelson, Maire, Rätsep, Ranno, Aunin, Eerik, Reimann, Ene, Reemann, Paula, Porosaar, Orm, Vikeså, Jonas, Nielsen, Finn C, Vasar, Eero, Silm, Helgi, Kõks, Sulev
• Format: Journal Article
• Language: English
• Published: BioMed Central Ltd 08.04.2010
• Subjects: Genetic aspects; Genetic polymorphisms; Genetic susceptibility; Mitochondrial DNA; Physiological aspects; Risk factors; Vitiligo; Denmark

MYG1 (Melanocyte proliferating gene 1, also C12orf10 in human) is a ubiquitous nucleo-mitochondrial protein, involved in early developmental processes and in adult stress/illness conditions. We recently showed that MYG1 mRNA expression is elevated in the skin of vitiligo patients. Our aim was to exa...